Blar i NTNU Open på forfatter "Flatekvål, Helene Midtun"
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cPLA2α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation
Ashcroft, Felicity; Mahammad, Nur; Flatekvål, Helene Midtun; Feuerherm, Astrid Jullumstrø; Johansen, Berit (Journal article, 2020)As a regulator of cellular inflammation and proliferation, cytosolic phospholipase A2 α (cPLA2α) is a promising therapeutic target for psoriasis; indeed, the cPLA2α inhibitor AVX001 has shown efficacy against plaque psoriasis ... -
Investigation into the effects of inhibiting cytosolic phospholipase A2 alpha on the proliferation of an immortalized keratinocyte cell line (HaCaT).
Flatekvål, Helene Midtun (Master thesis, 2020)Psoriasis er en vanlig kronisk inflammatorisk sykdom som er karakterisert ved hyperproliferering og unormal differensiering av epidemis. Det er ingen kur, og det har vært lite forbedring i utviklingen av nye behandlinger ...